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Donor Egg IVF by the Numbers
Donor eggs

Donor Egg IVF by the Numbers

by
Jessie Goldman
January 15, 2025
Last updated:
January 16, 2025
Photo of a person's hands typing on a tablet keyboard.

Making sense of fertility statistics can feel overwhelming, but numbers help tell the story of donor egg IVF in the United States. From success rates to costs, demographic trends to treatment guidelines, data provides valuable insights for those considering this path to parenthood. Let’s look at the numbers that shape donor egg IVF today.

10,000: Annual births from donor eggs

In 2021, nearly 10,000 babies were born in the United States through donor egg IVF. This represents approximately 1 in 373 births nationwide, highlighting how this treatment has become an established family-building option.

25%: Percent of IVF moms over 40 who used donor eggs

For women over 40 pursuing IVF, donor eggs often provide the best chance of success. Data shows that 25% of women in this age group who succeeded with IVF did so using donor eggs. This statistic reflects the significant impact of egg quality on treatment outcomes.

6: Components of medical screening

Comprehensive medical screening forms the foundation of successful donor egg IVF, typically requiring hours of medical appointments and evaluations spread over several weeks or months. This thorough process protects both donors and recipients while optimizing treatment success rates. Medical screening includes:

  • Genetic testing
  • Infectious disease screening
  • Psychological evaluation
  • Physical examination
  • Family medical history review
  • Fertility assessment

Read more in How Does Cofertility Screen Egg Donors?

54%: Live birth rates with fresh donor egg

This may sound low, but donor egg IVF has the highest success rate of any fertility treatment. For an average woman with diminished ovarian reserve, the chances of live birth after one donor egg cycle is 54% for recipients under 40. Rates of pregnancy with donor eggs are higher at every age. Several factors influence success:

  • Donor age and health status
  • Sperm quality
  • Recipient uterine health
  • Clinic protocols and expertise
  • Number of embryos transferred
  • Embryo quality

21-34: Age requirements for egg donors

The American Society for Reproductive Medicine (ASRM) sets clear age guidelines for egg donors:

  • Minimum age: 21 years old
  • Maximum age: 34 years old

These parameters aim to optimize success rates while protecting donor health and autonomy. The minimum age ensures donors can make informed decisions about participation, while the maximum age increases the chances there will be enough high quality eggs.

Read more in Why Egg Donor Age Matters (And Why It Doesn't)

6: Maximum number of egg donation cycles a donor should go through

The American Society for Reproductive Medicine (ASRM) recommends limiting donors to six egg retrieval cycles in their lifetime. This guideline stems from medical concerns about the cumulative effects of ovarian stimulation and retrieval procedures. 

Most donors at Cofertility complete two cycles, well within these safety parameters. This also limits the number of biological half siblings that your donor conceived children may have, a fact that’s important to many of our intended parents and donors alike. 

84.2%: Percent of donor egg embryos that are chromosomally normal

Research shows that 84.2% of donor egg blastocysts are chromosomally normal (euploid), while 15.8% are abnormal (aneuploid). Breaking down the numbers:

  • 97.1% egg survival rate after thaw
  • 59.1% of embryos reach the blastocyst stage
  • On average, 9 donor eggs yield about 4-5 chromosomally normal embryos

83.3%: Egg sharing donors who would donate again

Research on egg share donors' experiences reveals high satisfaction levels: 83.3% would donate again, while only 2.1% reported regret about their decision to participate. These numbers suggest that with proper screening and support, most egg share donors feel positive about their choice to help others build families.

62%: Portion of donor-conceived people who feel the exchange of money for donor gametes is wrong

A 2021 Harvard study found that 62% of donor-conceived adults felt the exchange of money for donor gametes was wrong, and 41% were troubled by the fact that money was exchanged around their conception. 

This is why we created our Split program.  This unique model empowers women to take control of their own reproductive health while giving you the gift of a lifetime. Our donors aren’t doing it for cash – they keep half the eggs retrieved for their own future use, and donate half to your family.

$5,000: Recommended compensation guidelines

The American Society for Reproductive Medicine suggests donor compensation should not exceed $5,000 per cycle in the United States. This contrasts sharply with European guidelines, where compensation averages around 900 euros per cycle. These differences reflect varying approaches to egg donation globally, from more commercial U.S. models to altruistic European frameworks. Despite this, compensation for egg donation has been steadily rising and can vary based on a donor’s education or heritage. 

At Cofertility, our program is unique in that our donors do not receive cash compensation. After meeting with hundreds of intended parents, egg donors, and donor-conceived people, we decided on an egg donation model that we think best serves everyone involved: egg sharing. By allowing our donors to freeze their eggs as part of the process, our unique model honors everyone involved. Plus, the process with Cofertility will never cost more based on the donor’s background. 

12: Average number of mature eggs a Cofertility family receives in our fresh Split program

In Cofertility’s fresh program, the average number of mature eggs a family receives and fertilizes is 12. Some intended parents want to do two egg retrievals with the donor which is definitely possible. We also ask each of our donors whether they are open to a second cycle as part of the initial application — many report that they are!

While you can agree to complete two cycles upfront, many matches who are interested in two cycles choose to see how many eggs are retrieved in the first cycle and go from there. If, for any reason, the eggs retrieved in that round do not lead to a live birth, our Baby Guarantee will kick in and we’ll re-match you at no additional Cofertility coordination fee.

Find an amazing egg donor at Cofertility

At Cofertility, our program is unique. After meeting with hundreds of intended parents, egg donors, and donor-conceived people, we decided on an egg donation model that we think best serves everyone involved: egg sharing.

Here’s how it works: our unique model empowers women to take control of their own reproductive health while giving you the gift of a lifetime. Our donors aren’t doing it for cash – they keep half the eggs retrieved for their own future use, and donate half to your family.

We aim to be the best egg-sharing program, providing an experience that honors, respects, and uplifts everyone involved. Here’s what sets us apart:

  • Human-centered. We didn’t like the status quo in egg donation. So we’re doing things differently, starting with our human-centered matching platform.
  • Donor empowerment. Our model empowers donors to preserve their own fertility, while lifting you up on your own journey. It’s a win-win.
  • Diversity: We’re proud of the fact that the donors on our platform are as diverse as the intended parents seeking to match with them. We work with intended parents to understand their own cultural values — including regional nuances — in hopes of finding them the perfect match.
  • Baby guarantee. We truly want to help you bring your baby home, and we will re-match you for free until that happens.
  • Lifetime support: Historically, other egg donation options have treated egg donor matching as a one-and-done experience. Beyond matching, beyond a pregnancy, beyond a birth…we believe in supporting the donor-conceived family for life. Our resources and education provide intended parents with the guidance they need to raise happy, healthy kids and celebrate their origin stories.

We are obsessed with improving the family-building journey — today or in the future — and are in an endless pursuit to make these experiences more positive. Create a free account to get started today!

Jessie Goldman

Jessie is Head of Partnerships at Cofertility, forging relationships with clinics and other strategic partners that support Cofertility members across their journeys. She joined Cofertility while in business school and came on full-time after graduation. Prior to business school, she worked in healthcare research and consulting, leading best practice research studies and advising medical device, pharmaceutical, and healthcare technology companies. Her passion for improving access to health care services stemmed from her experience as a health clinic volunteer, where she connected lower income patients with social services that could improve health outcomes. Jessie has a Bachelor of Arts (BA) in Economic History from the University of Pennsylvania and a Masters in Business Administration (MBA) from Columbia Business School with a focus in Healthcare and Pharmaceutical Management.

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