Is At-Home IUI Safe?

If you’ve listened to your reproductive endocrinologist explain the insemination process to you, there’s a chance you’re thinking, “That sounds simple enough...couldn’t I do that myself?” You’ve got sperm (or know where to get some). You’ve got a uterus. Do you really need to schedule a doctor’s appointment for this?

The answer, surprisingly, might be no — but only if you’re talking about artificial insemination, not its more complicated cousin, intrauterine insemination (IUI), which definitely has to be done by a medical professional. Here’s how the two procedures size up in comparison (and how to know which one is right for you). 

Artificial insemination vs. IUI: The basics

The short version: artificial insemination refers to the process of inserting ejaculate into the vagina, close to the cervix, using a needleless syringe (i.e. the “turkey baster” method...more on that later). It’s sometimes referred to as intracervical insemination (ICI). IUI, on the other hand, involves a speculum and the placement of sperm directly into the uterine cavity instead of the vaginal canal. 

The similarities

They both have the potential to get you pregnant. But here’s a few other ways they’re similar:

• No sex is required, which means that both ICI and IUI work as well for heterosexual couples as same-sex (or single women, or gay men working with a surrogate, or whatever). Pretty much anytime conception without intercourse is the goal, either procedure can be used. You just may need to work with a sperm or egg donor.
• Ovulation is key. Whichever method you choose, you’ll need to make sure that you’re within your fertile window. If you’re doing IUI at your fertility clinic, your doctor will help you track your ovulation leading up to that point (and/or prescribe you medication in order to induce ovulation) to figure out the best timing for the procedure. If you’re planning to DIY at home, you’ll need an OTC ovulation predictor kit to help you track your cycle and determine timing. 

Key differences 

All of that said, there are a few important differences between artificial insemination and in-office IUI:

• Know-how. IUI is best performed in a doctor’s office, because really, they know reproductive anatomy (and how to use a speculum) best. You’ll also need to be in a sterile environment in order to reduce the risk of infection. ICI, on the other hand, is fairly user-friendly, even for novices. 
• Unwashed vs. washed semen. If you haven’t been paying close attention thus far, heads up because this is important: never put an unwashed sample of sperm directly into your uterine cavity (seriously, like ever). The seminal fluid that bathes sperm contains something called prostaglandins, which — if placed inside the uterine cavity — can cause a severe reaction in the form of painful uterine contractions, warns Dr. Mark Trolice, a reproductive endocrinologist at The IVF Center. This seminal fluid is washed away in preparation for an in-office IUI, so it’s not an issue there. It’s totally fine to put unwashed semen into your vagina during an ICI (since that’s basically what happens during sex anyway), because it’s technically a different location. But if you injected unwashed semen into your uterus during an attempt at an at-home IUI, it would not be good. 

How does at-home insemination work?

Remember how we said at-home insemination was pretty foolproof (the process, not necessarily the “getting pregnant” part)? We weren’t lying. You grab some semenfrom your partner or sperm donor, and a home insemination kit, which usually includes ovulation predictor materials,  along with a plastic syringe and plunger that functions kind of like a turkey baster. Also, FYI: frozen sperm will have to be thawed briefly before use, but once it’s at room temperature (or if you’re starting with freshly ejaculated sperm), make sure to use it within 30 minutes. 

Once you have your syringe filled with semen, this is what you do:

1. Lie down on your back.
2. Insert the syringe into your vagina, pushing gently until it stops and aiming it toward your cervix.
3. Empty the syringe, then take it out. 
4. Chill out for 15 to 30 minutes. You’ll want to stay horizontal for a bit to make sure the sperm get where they need to go. (Note that this isn’t necessary for IUI: a 2016 study presented to the European Society of Human Reproduction and Embryology showed no significant difference in conception rates between women who lied down for 15 minutes after IUI vs. women who didn’t.)

That’s it! 

What’s the best at-home IUI kit?

If you’re definitely not moving forward with an in-office IUI, there are several options when it comes to at-home insemination. One of these is Mosie Baby, which actually calls themselves an at-home ICI kit. As we mentioned earlier, ICI kits deliver sperm directly at or near the cervical opening. 

Mosie’s syringes are specifically designed to release as much semen as possible at an optimal flow. They’re also shaped in a way that’s smooth, rounded, and more comfortable than other options. 

Mosie suggests using their kit at the first sign of ovulation (usually about 2-3 days before ovulation occurs). They also actually include a second syringe, which they recommend using 18-36 hours after the first one.

Mosie has simple, clear, easy-to-understand instructions (with graphics!) that explain exactly how to use the kit. Essentially, you follow the steps outlined above: collect a semen sample, transfer the sample into the syringe, insert the sample into your cervix, and then kick back, “relax” and start that oh-so-fun two-week wait. 

As an added bonus, CoFertility users can score 10% off Mosie Baby products when they click our link below and use code COFERTILITY. Happy inseminating! 

Which one is more likely to get me pregnant: at-home insemination or IUI?

At-home insemination is more convenient and private, plus you don’t have to involve your insurance company and the cost (for the kit) is minimal. But according to Dr. Trolice, if you’re considering the success rates of the two procedures, you’ll definitely want to stick with in-office IUI.

Essentially, washed sperm used for an in-office IUI places the best, fastest sperm directly into the uterus — much farther up than standard vaginal insemination. Overall, the American Pregnancy Association claims success rates for IUI can be as high as 20%, but take this with a grain of salt: this percentage totally depends on why you’re doing IUI in the first place, as well as the protocol of meds leading up to the procedure. 

Summing it up

Theoretically, if you personally know a midwife (or some other medical practitioner) who has access to a speculum AND you’ve purchased pre-washed sperm from a sperm bank, AND you’ve completely sterilized your home, then you could do an IUI in your living room — but that’s a lot of conditions to meet, so to us, it’s honestly just not worth the risk. But if you’re okay with the lower odds of pregnancy, a plain ol’ “turkey baster” ICI is way easier and less dangerous to do at home. Leave the IUIs to the professionals, please.