egg donation

Vaping has become a popular alternative to traditional smoking in recent years. But while it’s been marketed as a healthier option, the long-term effects of vaping are still not fully understood. One area of concern is the impact of vaping on fertility, especially for those who are considering freezing their eggs for future use. In this article, we’ll dive into the research on if vaping is okay for egg freezing and donation.

Impact of vaping on fertility

Several studies have found that vaping can have negative effects on reproductive health, including decreased fertility and increased risk of miscarriage. According to the American Society of Reproductive Medicine (ASRM), infertility rates in male and female smokers are twice as high as infertility rates among nonsmokers, with infertility rates rising with the number of cigarettes smoked daily. The main ingredients in e-cigarette liquids, such as nicotine and propylene glycol, have been shown to have toxic effects on the ovaries and the eggs they contain.

Nicotine has been shown to reduce the quality and quantity of eggs in the ovaries. It can also lead to decreased blood flow to the ovaries, which can negatively impact the development of the follicles, the structures in the ovaries that contain the eggs. Despite needing more medication during the egg freezing process, smokers often have fewer eggs available for retrieval during an egg freezing cycle, as well as 30% lower pregnancy rates compared with nonsmokers.

Propylene glycol, another common ingredient in e-cigarette liquids, has been shown to have a toxic effect on the ovaries and eggs. The same study has linked propylene glycol to oxidative stress, which can lead to damage to the eggs and decreased fertility. In addition, propylene glycol has been shown to cause DNA damage, which can affect the quality of the eggs.

How vaping may affect egg freezing outcomes

Egg freezing is a process where a woman's eggs are retrieved, frozen, and stored for later use once she is ready to fertilize them and start or grow her family. The more eggs that are retrieved, the better the chances of a live birth down the line. 

While the effects of vaping on fertility are still largely unknown, many fertility clinics advise their patients to quit vaping in an effort to improve egg freezing outcomes related to quality and quantity based on the above research on smoking. Lower quality eggs with a higher DNA damage rate could impact the success of a future pregnancy using these frozen eggs, as these eggs may be less likely to fertilize into embryos (or result in a successful implantation). In addition, fewer eggs retrieved from those who vaped may result in fewer options for future use, which can increase the likelihood of needing additional egg freezing cycles.

Our programs offer the opportunity to freeze your eggs in a way that’s more empowering, positive, and affordable — even free. Take our quiz today to see if you qualify for Split, our free egg freezing program. 

Can I donate my eggs if I vape? 

If you are considering applying for our Split program, where you can freeze your eggs for free when you donate half of the eggs retrieved to another family, please note that you will not be considered eligible if you currently use any nicotine products, including vaping. If you engage in vaping regularly, you will need to quit for two to three months before re-applying for the program. If you only vape occasionally/socially, you will need to quit for one month prior to your retrieval date.

Summing it up

In conclusion, while data is somewhat limited, it appears that the effects of vaping on fertility can have an impact on women who are considering egg freezing. The ingredients in e-cigarette liquids, such as nicotine and propylene glycol, have been shown to have negative effects on reproductive health, including decreased fertilization rates and increased risk of miscarriage. In addition, it is possible that vaping can lead to a lower number of eggs retrieved during an egg freezing cycle and a higher rate of DNA damage in the retrieved eggs. 

Our recommendation? Safe is better than sorry — in the interest of the best cycle outcome, it’s probably a good idea to hold off on the e-cigarettes leading up to and during your egg retrieval. 

If you’re considering egg freezing, consult with a fertility specialist or take our quiz to learn more about how you can preserve your fertility.

Has anyone ever told you that freezing your eggs will affect your ability to conceive naturally in the future? If you’ve heard this before, it’s understandable that it would make you think twice about pursuing egg freezing or donation. While this is a common question, it’s actually a misconception. Read on to learn more about why this is a myth and what egg freezing actually does for your fertility. 

The truth about egg freezing (or donation) and fertility

Let's get right to it—does freezing or donating eggs impact your ability to get pregnant on your own in the future? The short answer is no, egg freezing won’t lower your egg reserve and it won’t affect your chances of getting pregnant naturally when you’re ready to do so. To understand why this is, let’s talk about the ovulation process. 

What happens when you ovulate?

At the start of each menstrual cycle, when someone is on their period, their pituitary gland (in the brain) will release follicle stimulating hormone (FSH). FSH triggers fluid-filled sacs in both ovaries to grow. These sacs are called follicles and they each contain an egg. The follicles grow until a second signal from the brain forces only one follicle (the “dominant” follicle) to continue to mature and eventually release its egg. That egg being released is what we call ovulation. 

Now that that single egg has been ovulated, what happens to all the other eggs in those other follicles? Well, since those follicles weren’t chosen as the dominant follicle, they stop growing and the eggs inside of them die. This is known as atresia. So, it’s basically survival of the fittest in each ovary every month — yikes!

So what does all that have to do with egg freezing?

Let’s briefly review what the egg retrieval process is for egg freezing, donation, and in vitro fertilization (IVF). The hormone medications used during all three processes prompts your ovaries to allow all of the eggs in a single cycle to mature (instead of the usual one) so you can freeze them for if and when you might need them later on. 

Once the follicles have reached an appropriate size, the eggs are collected during a quick procedure in the office. This retrieval process happens under light sedation and involves using a vaginal ultrasound and a long needle with a suction device to retrieve the eggs. I promise this sounds much more intense than it actually is! An embryologist (an expert in the science of egg freezing) looks at each egg and grades their maturity before freezing them. If you’re doing IVF, they’ll go through fertilization instead of being frozen.  

Can I get pregnant unassisted after egg freezing?

What you may have noticed from what was just explained is that egg freezing actually rescues all the other eggs that your body would otherwise allow to die during a normal menstrual cycle. So the process of egg freezing doesn’t take anything away from your egg reserve, it actually helps you save some extra eggs! And since during each cycle, your body goes through the ovulation process again with a new set of competing eggs, your chances of getting pregnant unassisted in the future also aren’t affected by egg freezing. 

What egg freezing does do is give you additional options for if and when you’re ready to start growing your family.

Egg freezing actually rescues all the other eggs that your body would otherwise allow to die during a normal menstrual cycle. So egg freezing doesn’t take anything away from your egg reserve, it actually helps you save some extra eggs!

Can egg freezing damage my ovaries?

Like any other procedure, there are risks and side effects when freezing eggs, including risks of anesthesia, bleeding, pain, and infection. Thankfully, the majority of people who go through with it deal with side effects for a few days at most. When it comes to the ovaries themselves, they generally recover quickly. While there isn’t a lot of data specific to egg donors (as opposed to people freezing their eggs for themselves), the overall data indicate that the potential risks of surgical complications from egg retrieval are generally very small. However, in people with a history of endometriosis, pelvic inflammatory disease, pelvic adhesions or previous pelvic surgery, the risks are slightly increased so make sure to speak to your doctor about your medical history if you fall into any of these categories.

In terms of complications down the road, there are really two main ways by which egg retrieval might conceivably affect future fertility. The first way is by bleeding and infection from the procedure leading to adhesions (scar tissue) and the need for further surgeries. The second way is through trauma to the ovaries causing the creation of antibodies that may make fertilization of an egg more difficult.

Fortunately, there is no data that supports either possibility. According to one large study of over 7,000 IVF cycles, the rates of both infection and need for surgery to treat a pelvic abscess was 0.03% (about 1 in 3,000 IVF cycles). As for the scar tissue and antibodies, researchers have not found a higher rate of adhesions among people who have had an egg retrieval compared to those who haven’t nor have they found evidence that antibodies interfere with sperm’s ability to fertilize an egg. 

It’s up to you!

If you decide to go through with egg freezing, Freeze by Co is here to help. Our Split program allows those who qualify to freeze their eggs for free! In a Split cycle, you donate half of the eggs retrieved to a family that can’t otherwise conceive and freeze the remaining half for yourself. 

If you don’t want to donate, you can still participate in the Keep program, where you’ll be able to freeze your eggs and keep them all for yourself, on your timeline. In addition, you’ll have access to our online support community. This valuable resource lets you engage with other people freezing their eggs at the same time! 

Whatever you choose, our team is here to support you as you determine which family-building options are right for you!

Donating eggs can be a generous and life-changing decision for both the donor and the intended parent. If you have been interested in donating your eggs, you may be wondering if there’s an age cut-off. The short answer is, yes, there are age restrictions when it comes to donating eggs. In this article, we will discuss how old you have to be to donate your eggs and what factors may affect your eligibility.

What is the minimum age for egg donation?

American Society for Reproductive Medicine (ASRM) suggests that egg donors be at least 21 years of age at the time of donation. Most clinics and agencies follow this suggestion to ensure the donor is mature enough to understand the procedure and follow through on the commitment. 

To be part of our Split Program, where you freeze your eggs for free when donating half to a family that can’t otherwise conceive, you must be at least 21 years old. And while we do not accept Split members who are under 21, please reach out and we’ll get back in touch after you turn 21. 

What is the maximum age for egg donation?

While there is no legal maximum age to become an egg donor, ASRM recommends that donors be under the age of 34 and most clinics follow this guideline. 

At Cofertility, we require our Split program members to be 33 or under, as it can take some time to match with intended parents and complete your cycle. If you are 34-39, you are still eligible to participate in our Keep program. With this program, you can freeze your eggs and keep 100% of them for yourself. 

Why are their age requirements for egg donation? 

Because donor egg IVF is already so expensive and time consuming, families and clinics want to do everything they can to increase chances of success.

One factor that can predict success is age. Women in their 20s typically have a higher quantity and quality of eggs, making them ideal candidates for egg donation. Data shows that, on average, those over 35 tend not to respond to fertility medication as well and therefore may not produce as many eggs. Research also shows that, unfortunately, egg quality declines with age. 

Are there exceptions?

There are cases where a clinician may accept a known donor outside the recommended age range. For example, if someone wanted their 35-year-old sister to donate and she had recently undergone a successful egg retrieval, the doctor may approve her donation. 

Conclusion

Egg donation is a serious commitment and involves a significant time and energy commitment from the donor. The process typically involves several weeks of hormone injections, frequent doctor's appointments, and a minor surgical procedure to retrieve the eggs. 

While 21-34 is the recommended age for egg donation, keep in mind there are additional eligibility criteria. It is important for potential donors to carefully consider the risks and benefits and to ensure that they meet all of the eligibility criteria before making a decision.

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