

If you were adopted and are considering becoming an egg donor, you’ve probably come across the question: “Do you know your biological family’s medical history?” For many adoptees, the answer is no—and that can be a frustrating sticking point when you're otherwise healthy and eager to help someone build a family.
In this article, we’ll break down why biological family medical history is required in the egg donation process, how that impacts people who were adopted (especially in closed or international adoptions), and what your options are if you want to donate but don’t have access to that information. We’ll also touch on when an adopted person can donate, and when the lack of family history may be a disqualifier.
Whether you're adopted yourself or just trying to understand the egg donation process more clearly, this guide will give you the context you need to move forward with realistic expectations.
Why egg donation programs ask about biological family history
When someone applies to donate their eggs, fertility clinics and egg banks typically follow ASRM and FDA guidelines and ask for a detailed medical history—not just about the donor, but also about their biological family. This includes three generations of health information: parents, grandparents, siblings, aunts, uncles, and sometimes cousins.
This requirement exists for a few reasons. First, some medical conditions have a strong genetic component. Knowing if a donor’s family has a history of things like early-onset cancers, heart disease, autoimmune conditions, or hereditary syndromes helps clinics and recipients make more informed choices. Second, egg recipients are often looking for transparency—they’re making major decisions about their family and want as much information as possible about the donor's health background, including inherited risks that could affect the child.
To be clear, having health conditions in your family history doesn’t automatically disqualify you, but not having any biological family history usually does. That’s where it becomes an issue for many adopted people.
What this means if you’re adopted
If you were adopted and don’t have access to your biological family’s medical history, you may not be eligible to donate your eggs—at least not through most egg banks or egg sharing programs like Cofertility. The FDA and most clinics require that family history to approve someone as a donor. Without it, clinics can’t properly assess inherited health risks, which raises medical and ethical concerns for everyone involved.
This can be disappointing, especially if you’re otherwise in good health and motivated to help another family.
Are there any exceptions?
There are a few situations where adopted people can donate, but it depends on the circumstances:
- Open adoptions: If you have contact with your birth family or access to reliable medical information about them, you may be able to provide the necessary family history.
- Access to adoption records: In some states or countries, adopted people can request their original birth certificates or medical records. This may require a formal request through the state or adoption agency.
- Known donation with informed consent: In some cases, a known recipient—such as a friend or relative—may agree to proceed with egg donation despite the lack of biological family medical history. This usually involves a legal agreement where the recipient waives the right to detailed genetic history and acknowledges any potential risks. Not all clinics allow this, but some will accept it if both parties undergo legal and psychological counseling and the medical team signs off.
If you’re not sure how much information you have, it’s still worth reaching out. Some adopted donors find that they do have enough medical history to move forward after requesting records or talking to relatives. Others decide to explore options for egg freezing for their own use instead.
Why this requirement exists
It can feel unfair that being adopted—something you had no control over—could exclude you from donating eggs. But there’s a real reason behind the policy: it’s about protecting the health of the child who could be born from the donation, and ensuring that the recipient family has a clear picture of the potential genetic risks.
Donor-conceived children often want to know more about their genetic origins as they grow up, including health risks that might affect them. Having a documented medical history helps provide that transparency. Without it, future medical care for the child could be more complicated.
Clinics and egg donation programs have a responsibility to both recipients and potential offspring—not just donors. That’s why the requirements are as strict as they are.
What are your options if you can’t donate?
If you're adopted and don't have access to biological family history, you likely won’t qualify to donate your eggs right now. But that doesn't mean you're out of options entirely.
You might consider:
- Freezing your eggs for your own future use. With our Keep program, you can more affordably freeze your eggs with partnerships that lighten the financial load and ongoing support from our team.
- Exploring whether you can get more information. If your adoption was semi-open or records are available through your state or country, you may be able to gather enough information to meet donation requirements.
- Checking back in the future. Some people gain access to their biological history later in life, either through DNA testing, ancestry sites, or contact with biological family members. If that happens, you may be able to revisit the idea of donation.
The bottom line
If you’re adopted and don’t have access to your biological family’s medical history, you probably won’t be able to donate your eggs. That’s not a reflection on you—it’s a safeguard built into the process to protect intended parents and future children.
Still, your desire to help others grow their families is something to be proud of. If you do gain access to your biological medical history down the line, egg donation may still be a possibility. In the meantime, freezing your eggs for yourself is absolutely an option, and we’re here to support you however you decide to move forward.
